1916 Bishop Schrembs formally requests a Toledo Province of Rochester Sisters. On November 23, Rochester Franciscans were selected as the original province members. The group was under the direction of Mother Adelaide Sandusky, the newly appointed Provincial Superior.
1917 Three farms located in Sylvania, Ohio, are purchased. This property would one day become the home of the Franciscan Sisters.
1942 An extension campus of St. Teresa in Winona, Minnesota, is established on the Sylvania-Franciscan campus.
1958 Lourdes Junior College is founded. Mother Justinian Warpeha, OSF is the first President (1958-1962).
1964 The College receives accreditation from the North Central Association of Colleges and Schools during the presidency of Sr. M. Remigia Kostick, OSF, 1962–1972.
1969 Lay women are admitted to the Junior College.
1973 Lourdes College becomes independently incorporated.
1975 During the presidency of Sr. Rosaria Petra, OSF, 1972–1981, the first men are admitted to Lourdes College. Educational opportunities are also extended to students from the St. Vincent School of Nursing in Toledo and the Providence School of Nursing in Sandusky, Ohio.
1977 The Franciscan Sisters and area business and civic leaders hold extensive discussions regarding the need for a Catholic college following the closing of Mary Manse College. These discussions lead to a feasibility study regarding a four-year college.
1978 An Associate Degree for Occupational Therapy Assistant receives approval.
1979 A Lifelong Learning Center is founded by Sr. Ann Francis Klimkowski, OSF, and offers a wide range of adult education classes.
1981 Under the guidance of Sr. Marie Andrée Chorzempa, OSF, (acting president 1981–1983), the first bachelor’s degree programs are developed in religious studies and individualized studies. The Board approves the move to a four-year college.
1982 The College is authorized by the Ohio Board of Regents and receives accreditation from North Central Association for baccalaureate degrees.
1983 Sr. Ann Francis Klimkowski, OSF, becomes president of the College (1983–2000).
1986 Two more bachelor’s degrees are added to the curriculum: Bachelor of Arts and Bachelor of Science in Nursing.